Invention Publication
- Patent Title: TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT
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Application No.: US18082812Application Date: 2022-12-16
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Publication No.: US20230173071A1Publication Date: 2023-06-08
- Inventor: John B. JARMAN , Dennis A. DOUGHERTY , Robert H. GRUBBS , Christopher B. MAROTTA , Daniel M. SCHWARTZ
- Applicant: California Institute of Technology , The Regents Of the University of California , U.S. Government represented by the Development of Veterans Affairs
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology,The Regents Of the University of California,U.S. Government represented by the Development of Veterans Affairs
- Current Assignee: California Institute of Technology,The Regents Of the University of California,U.S. Government represented by the Development of Veterans Affairs
- Current Assignee Address: US CA Pasadena
- Main IPC: A61K41/00
- IPC: A61K41/00 ; A61P27/02
Abstract:
This current disclosure is directed to compositions based on certain heptamethine dyes useful for generating singlet oxygen using NIR radiation, optionally comprising additives and solvents that enhance the performance of these dyes, and procedures using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use near-infrared irradiation to improve the mechanical strength of the sclera.
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