公开(公告)号：US20230173071A1

公开(公告)日：2023-06-08

申请号：US18082812

申请日：2022-12-16

Applicant: California Institute of Technology ,  The Regents Of the University of California ,  U.S. Government represented by the Development of Veterans Affairs

Inventor： John B. JARMAN ,  Dennis A. DOUGHERTY ,  Robert H. GRUBBS ,  Christopher B. MAROTTA ,  Daniel M. SCHWARTZ

IPC: A61K41/00 ,  A61P27/02

CPC classification number: A61K41/0057 ,  A61P27/02

Abstract: This current disclosure is directed to compositions based on certain heptamethine dyes useful for generating singlet oxygen using NIR radiation, optionally comprising additives and solvents that enhance the performance of these dyes, and procedures using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use near-infrared irradiation to improve the mechanical strength of the sclera.