- 专利标题: ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF
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申请号: US17702597申请日: 2022-03-23
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公开(公告)号: US20230183239A1公开(公告)日: 2023-06-15
- 发明人: William Michael GALLATIN , Joshua ODINGO , Gregory N. DIETSCH , Vincent FLORIO , Chandregowda VENKATESHAPPA , Athisayamani Jeyaraj DURAISWAMY
- 申请人: AbbVie Inc.
- 申请人地址: US IL North Chicago
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: US IL North Chicago
- 主分类号: C07D471/10
- IPC分类号: C07D471/10 ; C07D211/28 ; C07D215/233 ; C07D215/44 ; C07D239/88 ; C07D239/94 ; C07D241/42 ; C07D307/81 ; C07D311/22 ; C07D401/04 ; C07D401/14 ; C07D405/14 ; C07D409/12 ; C07D413/14 ; C07D471/04 ; C07D487/04 ; C07D519/00 ; C07F5/02
摘要:
Disclosed herein are methods and compounds of augmenting and enhancing the production of type I IFNs in vivo. In some embodiments, the compounds disclosed herein are ENPP-1 inhibitors, pharmaceutical compositions, and methods for the treatment of cancer or a viral infection.
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