- 专利标题： COMPOSITIONS OF ADENOSINE DEAMINASE-2 (ADA2), VARIANTS THEREOF AND METHODS OF USING SAME
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申请号： US18059135申请日： 2022-11-28
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公开(公告)号： US20230203470A1公开(公告)日： 2023-06-29
- 发明人: Christopher D. THANOS , Lin WANG , H. Michael SHEPARD
- 申请人： Halozyme, Inc.
- 申请人地址： US CA San Diego
- 专利权人： Halozyme, Inc.
- 当前专利权人： Halozyme, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： C12N9/78
- IPC分类号： C12N9/78 ; A61K38/48
摘要：
Provided are variant adenosine deaminase 2 (ADA2) proteins, conjugates thereof and compositions containing the proteins and/or conjugates. Also provided are methods and uses of the ADA2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.
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