专利检索 ap:("Halozyme, Inc.") AND inv:"Lin WANG" 第 1 页

1.

发明公开
COMPOSITIONS OF ADENOSINE DEAMINASE-2 (ADA2), VARIANTS THEREOF AND METHODS OF USING SAME 审中-公开

公开(公告)号：US20230203470A1

公开(公告)日：2023-06-29

申请号：US18059135

申请日：2022-11-28

申请人： Halozyme, Inc.

发明人： Christopher D. THANOS , Lin WANG , H. Michael SHEPARD

IPC分类号： C12N9/78 , A61K38/48

CPC分类号： C12N9/78 , C12Y305/04004 , A61K38/48 , A61K38/00

摘要： Provided are variant adenosine deaminase 2 (ADA2) proteins, conjugates thereof and compositions containing the proteins and/or conjugates. Also provided are methods and uses of the ADA2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.