- Patent Title: METHOD FOR OBTAINING A MAMMALIAN CELL LINE THAT EXPRESSES A RECOMBINANT EQUINE CHORIONIC GONADOTROPIN (RECG), THE RECOMBINANT CELL LINES PRODUCING RECG, LARGE-SCALE RECG PRODUCTION METHOD, RECG, FORMULATIONS CONTAINING RECG, NUCLEIC ACIDS ENCODING FOR RECG AND USES
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Application No.: US17790385Application Date: 2020-12-23
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Publication No.: US20230242608A1Publication Date: 2023-08-03
- Inventor: Natalia Ceaglio , Claudio Prieto , Diego Fontana , Celeste Rodriguez , Belén Tardivo , Sebastián Antuna
- Applicant: Natalia CEAGLIO , UNIVERSIDAD NACIONAL DEL LITORAL , CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) , BIOTECNOFE S.A.
- Applicant Address: AR Santo Tome, Santa Fe
- Assignee: Natalia CEAGLIO,UNIVERSIDAD NACIONAL DEL LITORAL,CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET),BIOTECNOFE S.A.
- Current Assignee: Natalia CEAGLIO,UNIVERSIDAD NACIONAL DEL LITORAL,CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET),BIOTECNOFE S.A.
- Current Assignee Address: AR Santo Tome, Santa Fe
- Priority: AR 0190103911 2019.12.30
- International Application: PCT/EP2020/087779 2020.12.23
- Date entered country: 2022-06-30
- Main IPC: C07K14/59
- IPC: C07K14/59 ; C12N15/86 ; A61P15/08 ; A61K9/19
Abstract:
The present invention describes a method for obtaining a mammalian cell line that expresses a recombinant equine chorionic gonadotropin (reCG) hormone. A cell line expressing reCG, a large-scale method for producing reCG, a reCG with a higher biological activity regarding PMSG, formulations containing reCG, nucleic acids encoding reCG and uses are also described.
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