公开(公告)号：US20230242608A1

公开(公告)日：2023-08-03

申请号：US17790385

申请日：2020-12-23

Applicant: Natalia CEAGLIO ,  UNIVERSIDAD NACIONAL DEL LITORAL ,  CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) ,  BIOTECNOFE S.A.

Inventor： Natalia Ceaglio ,  Claudio Prieto ,  Diego Fontana ,  Celeste Rodriguez ,  Belén Tardivo ,  Sebastián Antuna

IPC: C07K14/59 ,  C12N15/86 ,  A61P15/08 ,  A61K9/19

CPC classification number: C07K14/59 ,  C12N15/86 ,  A61P15/08 ,  A61K9/19 ,  C12N2740/16043 ,  A61K38/00

Abstract: The present invention describes a method for obtaining a mammalian cell line that expresses a recombinant equine chorionic gonadotropin (reCG) hormone. A cell line expressing reCG, a large-scale method for producing reCG, a reCG with a higher biological activity regarding PMSG, formulations containing reCG, nucleic acids encoding reCG and uses are also described.