A method comprising receiving a blood pressure waveform from a sensor and deriving initial values. The method may further comprise deriving a diastolic transit time (DTT) value and a plurality of additional properties from the waveform. The method may further comprise calculating a calibration factor based on the DTT values and the additional properties. The method may further comprise calculating estimated DBP values based on the calibration factor, the DTT values, and the additional properties. The method may further comprise deriving an offset value based on a difference between the estimated DBP values and the raw DBP values, adjusting the blood pressure waveform based on the offset to generate an adjusted blood pressure waveform, and outputting the adjusted blood pressure waveform.