Invention Application
- Patent Title: MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 3-HYDROXYISOBUTYRATE OR METHACRYLIC ACID RELATED THERETO
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Application No.: US17833695Application Date: 2022-06-06
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Publication No.: US20230136909A1Publication Date: 2023-05-04
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Cara Ann Tracewell , Priti Pharkya , Stefan Andrae
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Main IPC: C12N15/52
- IPC: C12N15/52 ; C12P7/42 ; C08F120/06 ; C08G63/664 ; C12N15/63 ; C12P7/24 ; C12P7/40 ; C12N9/04 ; C12N9/06 ; C12N9/10 ; C12P7/62
Abstract:
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.
Information query
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