Invention Publication
![PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF](/docs/US/2024-01-11/US20240010656A1/abs.jpg.600x600.jpg)
- Patent Title: PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
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Application No.: US18369272Application Date: 2023-09-18
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Publication No.: US20240010656A1Publication Date: 2024-01-11
- Inventor: Ayman Allian , Jayanthy Jayanth , Mohamed-Eslam F. Mohamed , Mathew M. Mulhern , Fredrik Lars Nordstrom , Ahmed A. Othman , Michael J. Rozema , Lakshmi Bhagavatula , Patrick J. Marroum , Peter T. Mayer , Ahmad Y. Sheikh , Thomas B. Borchardt , Ben Klünder , Heidi S. Camp , Robert J. Padley , Jeffrey W. Voss
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicagp
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicagp
- Main IPC: C07D487/14
- IPC: C07D487/14 ; A61K9/00 ; A61K31/4985 ; A61K47/12 ; A61K47/38
![PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF](/abs-image/US/2024/01/11/US20240010656A1/abs.jpg.150x150.jpg)
Abstract:
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.
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