Systems and methods disclosed herein relate to acknowledgement signaling sent by a user equipment (UE) in response to downlink control information (DCI) received from a base station that schedules the use of multiple physical uplink control channels (multi-PUSCH) or multiple physical downlink control channels (multi-PDSCH). Acknowledgement signaling may inform the base station that DCI scheduling the multi-PUSCH/multi-PDSCH was received (or not), so that the base station may reclaim those scheduled resources in the case that the UE remains unaware of them. Methods for performing this signaling include, e.g., the use of HARQ-ACK codebooks (whether in a semi-static or dynamic manner), and aperiodic sounding reference signals (A-SRS). Embodiments involving such DCI received across multiple component carriers of different serving cells of the UE are contemplated. Acknowledgment signaling according to multi-PUSCH/multi-PDSCH subgroups, monitoring windows, acknowledgment signaling enablement/disablement, and the use of DCI to trigger acknowledgment signaling are also discussed.