- 专利标题: ATP-PRT VARIANT WITH REDUCED FEEDBACK INHIBITION BY HISTIDINE, AND HISTIDINE-PRODUCING STRAIN EXPRESSING SAME
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申请号: US18269689申请日: 2021-04-26
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公开(公告)号: US20240060103A1公开(公告)日: 2024-02-22
- 发明人: Jong Yun HAN , Chel Min YANG , Yong Soo KIM , Young Il JO
- 申请人: DAESANG CORPORATION
- 申请人地址: KR Seoul
- 专利权人: DAESANG CORPORATION
- 当前专利权人: DAESANG CORPORATION
- 当前专利权人地址: KR Seoul
- 优先权: KR 20200184683 2020.12.28
- 国际申请: PCT/KR2021/005243 2021.04.26
- 进入国家日期: 2023-06-26
- 主分类号: C12P17/10
- IPC分类号: C12P17/10 ; C12N9/10
摘要:
The present invention relates to an E. coli hisG-derived ATP-phosphoribosyltransferase variant having a reduced feedback inhibition by histidine and a strain expressing the same. The variant may maintain its activity even at a high histidine concentration, thus increasing histidine production.
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