发明公开
- 专利标题： NOVEL CARBOHYDRATE ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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申请号： US18264563申请日： 2022-02-09
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公开(公告)号： US20240084040A1公开(公告)日： 2024-03-14
- 发明人: Jiann-Shiun LAI , Hui-Wen CHANG , Yin-Chieh KUO , Chi-Sheng HSIA , Woan Eng CHAN , Ming-Tain LAI
- 申请人： OBI PHARMA, INC.
- 申请人地址： TW TAIPEI CITY
- 专利权人： OBI PHARMA, INC.
- 当前专利权人： OBI PHARMA, INC.
- 当前专利权人地址： TW TAIPEI CITY
- 国际申请： PCT/US2022/015834 2022.02.09
- 进入国家日期： 2023-11-17
- 主分类号： C07K16/46
- IPC分类号： C07K16/46 ; A61P35/00
摘要：
The present invention provides antibody or the antigen-binding portion thereof bind to carbohydrate antigen, such as Globo series antigens (e.g. Globo H, SSEA-4 or SSEA-3). Also disclosed herein are pharmaceutical compositions and methods for the inhibition of cancer cells in a subject in need thereof. The pharmaceutical compositions comprise an antibody or an antigen-binding portion thereof and at least one pharmaceutically acceptable carrier.
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