Invention Publication
- Patent Title: D-AMINO ACID OXIDASE MUTANTS AND USES THEREOF IN PREPARING L-GLUFOSINATE
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Application No.: US18469527Application Date: 2023-09-18
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Publication No.: US20240101974A1Publication Date: 2024-03-28
- Inventor: Dongzhi WEI , Hualei WANG , Chengjun WU , Qinghai LIU , Jian ZHANG , Zhonghua LUO , Changlei ZHANG
- Applicant: YONGNONG BIOSCIENCES CO., LTD. , EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY , NINGXIA YONGNONG BIOSCIENCES CO., LTD.
- Applicant Address: CN Shaoxing
- Assignee: YONGNONG BIOSCIENCES CO., LTD.,EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,NINGXIA YONGNONG BIOSCIENCES CO., LTD.
- Current Assignee: YONGNONG BIOSCIENCES CO., LTD.,EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,NINGXIA YONGNONG BIOSCIENCES CO., LTD.
- Current Assignee Address: CN Shaoxing; CN Shanghai; CN Yinchuan
- Priority: CN 2110475247.9 2021.04.29
- Main IPC: C12N9/06
- IPC: C12N9/06 ; C12N9/08 ; C12N15/70 ; C12P13/04

Abstract:
Embodiments of the present disclosure relate to a D-amino acid oxidase mutant and application in preparing L-glufosinate thereof. The D-amino acid oxidase mutant has an amino acid substitution at at least one of position 62 and position 226 of an amino acid sequence of the D-amino acid oxidase mutant when compared to an amino acid sequence of a D-amino acid oxidase as set forth in SEQ ID NO. 1, the position 62 and position 226 being defined with reference to SEQ ID NO. 1, and the amino acid sequence of the D-amino acid oxidase mutant having at least 90% identity to SEQ ID NO. 1.
Public/Granted literature
- US12060584B2 D-amino acid oxidase mutants and uses thereof in preparing L-glufosinate Public/Granted day:2024-08-13
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