- 专利标题： RECOMBINANT AAV1, AAV5, AND AAV6 CAPSID MUTANTS AND USES THEREOF
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申请号： US18164942申请日： 2023-02-06
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公开(公告)号： US20240109938A1公开(公告)日： 2024-04-04
- 发明人: George Vladimirovich Aslanidi , Kim M. Van Vliet , Mavis Agbandje-McKenna , Arun Srivastava
- 申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INCORPORATED
- 申请人地址： US FL GAINESVILLE
- 专利权人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
- 当前专利权人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
- 当前专利权人地址： US FL GAINESVILLE
- 分案原申请号： US17174587 2021.02.12
- 主分类号： C07K14/005
- IPC分类号： C07K14/005 ; C12N15/86 ; C12N15/861
摘要：
Provided herein are modified recombinant adeno-associated virus (rAAV) capsid proteins, such as modified rAAV1, rAAV5, and rAAV6 capsid proteins, rAAV particles comprising such capsid proteins, nucleic acid molecules encoding such capsid proteins, as well as compositions, kits and methods of use thereof.
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