- 专利标题: HUNTINGTIN MIMETIC PROTEIN-LIKE POLYMERS AND USES THEREOF
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申请号: US18452059申请日: 2023-08-18
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公开(公告)号: US20240110004A1公开(公告)日: 2024-04-04
- 发明人: Nathan C. GIANNESCHI , Mara A. FATTAH , Wonmin CHOI , Xin QI
- 申请人: Northwestern University , The Regents of the University of California , Case Western Reserve University
- 申请人地址: US IL Evanston
- 专利权人: Northwestern University,The Regents of the University of California,Case Western Reserve University
- 当前专利权人: Northwestern University,The Regents of the University of California,Case Western Reserve University
- 当前专利权人地址: US IL Evanston
- 主分类号: C08G61/08
- IPC分类号: C08G61/08 ; A61K31/787 ; A61P25/28
摘要:
Disclosed are protein-like polymers and uses thereof. The protein-like polymers generally comprise a polymer of formula (FX1) or (FX2). The polymer of formula (FX1) or (FX2) in some aspects inhibits the protein-protein interaction between VCP and mutant-type Huntingtin protein.
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