专利检索 ap:("Northwestern University" OR "The Regents of the University of California" OR "Case Western Reserve University") AND inv:"Xin QI" 第 1 页

1.

发明公开
HUNTINGTIN MIMETIC PROTEIN-LIKE POLYMERS AND USES THEREOF 审中-公开

公开(公告)号：US20240110004A1

公开(公告)日：2024-04-04

申请号：US18452059

申请日：2023-08-18

申请人： Northwestern University , The Regents of the University of California , Case Western Reserve University

发明人： Nathan C. GIANNESCHI , Mara A. FATTAH , Wonmin CHOI , Xin QI

IPC分类号： C08G61/08 , A61K31/787 , A61P25/28

CPC分类号： C08G61/08 , A61K31/787 , A61P25/28 , C08G2261/122 , C08G2261/149 , C08G2261/228 , C08G2261/3342 , C08G2261/418

摘要： Disclosed are protein-like polymers and uses thereof. The protein-like polymers generally comprise a polymer of formula (FX1) or (FX2). The polymer of formula (FX1) or (FX2) in some aspects inhibits the protein-protein interaction between VCP and mutant-type Huntingtin protein.