Invention Publication
- Patent Title: METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES
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Application No.: US18453987Application Date: 2023-08-22
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Publication No.: US20240124904A1Publication Date: 2024-04-18
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Priti Pharkya , Tae Hoon Yang , Jungik Choi
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Main IPC: C12P7/18
- IPC: C12P7/18 ; C07K14/245 ; C12N1/20 ; C12N9/00 ; C12N9/02 ; C12N9/12 ; C12N9/16 ; C12N9/52 ; C12N9/88 ; C12N15/52 ; C12P7/42

Abstract:
−The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at least a second attenuation of a succinyl-CoA converting enzyme or a gene encoding a succinate producing enzyme within a multi-step pathway having a net conversion of succinyl-CoA to succinate.
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