- 专利标题： TRICYCLIC UREA COMPOUNDS AS JAK2 V617F INHIBITORS
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申请号： US18237535申请日： 2023-08-24
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公开(公告)号： US20240150354A1公开(公告)日： 2024-05-09
- 发明人: Yanran Ai , Onur Atasoylu , Yu Bai , Joseph Barbosa , David M. Burns , Daniel Levy , Brent Douty , Hao Feng , Leah C. Konkol , Cheng-Tsung Lai , Xun Liu , Song Mei , Jun Pan , Haisheng Wang , Liangxing Wu , Wenqing Yao , Eddy W. Yue
- 申请人： Incyte Corporation
- 申请人地址： US DE Wilmington
- 专利权人： Incyte Corporation
- 当前专利权人： Incyte Corporation
- 当前专利权人地址： US DE Wilmington
- 主分类号： C07D471/14
- IPC分类号： C07D471/14 ; C07D519/00
摘要：
The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.
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