- 专利标题： LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT
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申请号： US18472875申请日： 2023-09-22
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公开(公告)号： US20240165066A1公开(公告)日： 2024-05-23
- 发明人: Richard Louis Dunbar , James Moberly , Richard Preston Mason
- 申请人： Amarin Pharmaceuticals Ireland Limited
- 申请人地址： IE Dublin
- 专利权人： Amarin Pharmaceuticals Ireland Limited
- 当前专利权人： Amarin Pharmaceuticals Ireland Limited
- 当前专利权人地址： IE Dublin
- 主分类号： A61K31/202
- IPC分类号： A61K31/202 ; A61K31/5575 ; A61K31/685 ; A61P11/00
摘要：
Provided are compositions comprising one or more polyunsaturated fatty acids or derivatives thereof, a source of phospholipid, and optionally one or more additional emulsifiers, as well as methods of using the same to treat various diseases. In some embodiments, provided is a lymph-releasing composition of eicosapentaenoic acid ethyl ester (LR-EtEPA) and methods of using the same to increase EPA uptake in tissues and to treat various diseases including cardiopulmonary diseases, renal diseases, neurological diseases, and cancer.
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