- 专利标题: USE OF FIBRONECTIN IN PREDICTING PREECLAMPSIA
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申请号: US18391104申请日: 2023-12-20
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公开(公告)号: US20240280589A1公开(公告)日: 2024-08-22
- 发明人: Isabella Caniggia , Martin Post , Sruthi Alahari
- 申请人: Sinai Health System , The Hospital for Sick Children
- 申请人地址: CA Toronto
- 专利权人: Sinai Health System,The Hospital for Sick Children
- 当前专利权人: Sinai Health System,The Hospital for Sick Children
- 当前专利权人地址: CA Toronto
- 主分类号: G01N33/68
- IPC分类号: G01N33/68
摘要:
A method and kit for predicting preeclampsia is provided. Levels of Jumonji C domain containing protein 6 (JMJD6) and fibronectin are measured in placenta-derived small extracellular vesicles isolated from a subject. The levels of JMJD6 and fibronectin are compared to a non-preeclamptic control. If levels of JMJD6 are depressed and levels of fibronectin are elevated, the subject may be monitored or treated for preeclampsia.
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