Invention Publication
- Patent Title: RETARGETED RETROVIRAL VECTORS RESISTANT TO VACCINE-INDUCED NEUTRALIZATION AND COMPOSITIONS OR METHODS OF USE THEREOF
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Application No.: US18667761Application Date: 2024-05-17
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Publication No.: US20240307555A1Publication Date: 2024-09-19
- Inventor: Kepler MEARS , Robert MANGUSO , Kathleen YATES , Kyrellos IBRAHIM , Peter ALLEN
- Applicant: The Broad Institute, Inc. , The General Hospital Corporation
- Applicant Address: US MA Cambridge
- Assignee: The Broad Institute, Inc.,The General Hospital Corporation
- Current Assignee: The Broad Institute, Inc.,The General Hospital Corporation
- Current Assignee Address: US MA Cambridge; US MA Boston
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K47/68 ; A61K47/69 ; A61P35/00 ; C07K14/005 ; C12N15/86
Abstract:
The invention features pseudotyped viral particles (e.g., lentiviral or gammaretroviral particles) and compositions and methods of use thereof, where the viral particles comprise a VHH domain.
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