Invention Application
- Patent Title: ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS
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Application No.: US18557876Application Date: 2022-04-28
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Publication No.: US20250092392A1Publication Date: 2025-03-20
- Inventor: Vinod VATHIPADIEKAL , Branko MITASEV , Courtney EASLEY-NEAL , Hyeong Wook CHOI , Francis G. FANG , John WANG , Praveen VEMULA , Jung Hwa LEE
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- International Application: PCT/US2022/026760 WO 20220428
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
Novel antisense oligonucleotides that induce Exon-2 skipping in the CD33 gene during pre-mRNA splicing, and their use in the treatment of a neurodegenerative disease, such as Alzheimer's disease, are disclosed.
Information query
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