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公开(公告)号：US20250092392A1
公开(公告)日：2025-03-20
申请号：US18557876
申请日：2022-04-28
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Vinod VATHIPADIEKAL , Branko MITASEV , Courtney EASLEY-NEAL , Hyeong Wook CHOI , Francis G. FANG , John WANG , Praveen VEMULA , Jung Hwa LEE
IPC: C12N15/113
Abstract: Novel antisense oligonucleotides that induce Exon-2 skipping in the CD33 gene during pre-mRNA splicing, and their use in the treatment of a neurodegenerative disease, such as Alzheimer's disease, are disclosed.
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