1-Azacyclopentano(1,2-a)adamantane compounds and derivatives thereof which have antiviral and anti-inflammatory properties and which are useful cardiovascular agents may be prepared starting from 2-adamantanones or substituted 2-adamantanones and proceeding through a series of intermediate compounds to the corresponding 1-azacyclopentano(1,2-a)-adamantanes. Derivatives may be obtained by reacting the latter with an alkyl or alkenyl halide, haloalkylamine or a haloalkyl substituted amine, a haloalkylcarboxylic acid, an aralkyl halide of up to 10 carbon atoms, or a haloalkyladamantylamine or haloalkyl substituted adamantylamine. The 2-adamantane alkylamine intermediates for the 1-azacyclopentano-(1,2-a)adamantane compounds also have antiviral and anti-inflammatory properties and are useful cardiovascular agents.