Invention Grant
- Patent Title: Tetrahydropyrid-4-yl-chroman-5-ol derivatives
- Patent Title (中): 四氢吡喃-4-基 - 苯并二氢吡喃-5-醇衍生物
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Application No.: US504087Application Date: 1974-09-09
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Publication No.: US3960880APublication Date: 1976-06-01
- Inventor: Charles Sylvester Fake
- Applicant: Charles Sylvester Fake
- Applicant Address: EN
- Assignee: Beecham Group Limited
- Current Assignee: Beecham Group Limited
- Current Assignee Address: EN
- Priority: UK13231/74 19740326; UK29638/74 19740704
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D405/04 ; C07G11/00 ; C07D211/68
Abstract:
Compounds of the formula: ##SPC1##And their pharmaceutically acceptable non-toxic salts, wherein R.sub.1 is alkyl of 5 to 8 carbon atoms which is straight chained or .alpha.-substituted by a methyl group or .alpha.,.alpha.-disubstituted by methyl groups and R.sub.5 is hydrogen, R.sub.6 or CO.R.sub.6 wherein R.sub.6 is alkyl of 1 to 4 carbon atoms or alkyl of 1 to 4 carbon atoms substituted by NR.sub.7 R.sub.8 wherein R.sub.7 and R.sub.8 are each hydrogen or alkyl of 1 to 4 carbon atoms or NR.sub.7 R.sub.8 is pyrrolidino, piperidino or morpholino, have been found to possess good antihypertensive activity while being of low-toxicity and substantially free of sedative side effects.
Public/Granted literature
- US5096938A Radiation-curable acrylates Public/Granted day:1992-03-17
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