发明授权
- 专利标题： Certain amino-nicotinamide derivatives
- 专利标题（中）： 某些氨基 - 烟酰胺衍生物
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申请号： US615452申请日： 1975-09-22
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公开(公告)号： US3970663A公开(公告)日： 1976-07-20
- 发明人: Gilbert Regnier , Roger Canevari , Xavier Pascaud
- 申请人： Gilbert Regnier , Roger Canevari , Xavier Pascaud
- 申请人地址： FR Suresnes
- 专利权人： Science Union et Cie, Societe Francaise de Recherche Medical
- 当前专利权人： Science Union et Cie, Societe Francaise de Recherche Medical
- 当前专利权人地址： FR Suresnes
- 优先权： UK20842/73 19730502
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D401/12 ; C07D403/12 ; C07D213/56
摘要：
Heterocyclic amides of the formula: ##EQU1## wherein: X is N or CH;n is O or 1 andR is ##EQU2## wherein: R.sub.1 is hydrogen or methyl, R.sub.2 and R.sub.3 which are the same, are lower alkyl or joined together, represent a polymethylenic chain from C.sub.4 to C.sub.7 optionally including an oxygen atom, andR' is saturated or unsaturated acyclic hydrocarbon radicals from C.sub.1 to C.sub.20, cycloalkyl from C.sub.3 to C.sub.7, Ar - A- or ##EQU3## wherein: A is a single bond or a saturated or unsaturated acyclic hydrocarbon chain from C.sub.1 to C.sub.6 optionally including an oxygen atom, andAr and R" are aromatic, alkoxy aromatic, methylenedioxy aromatic or polymethylenedioxy aromatic.These compounds are used as medicine, especially in the treatment of gastric hypersecretion, gastroduodenal ulcers and central nervous system disorders.
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