发明授权
- 专利标题： Process for N-acylation of 7 amino cephem compounds
- 专利标题（中）： 7个氨基头孢烯化合物的N-酰化方法
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申请号： US549807申请日： 1975-02-13
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公开(公告)号： US3988326A公开(公告)日： 1976-10-26
- 发明人: Shigeo Seki , Shingo Sugimoto , Shokichi Nakajima
- 申请人： Shigeo Seki , Shingo Sugimoto , Shokichi Nakajima
- 申请人地址： JA Tokyo
- 专利权人： Meiji Seika Kaisha, Ltd.
- 当前专利权人： Meiji Seika Kaisha, Ltd.
- 当前专利权人地址： JA Tokyo
- 优先权： JA49-20420 19740222; JA49-31001 19740320; JA49-41776 19740416
- 主分类号： C07D213/70
- IPC分类号： C07D213/70 ; C07D257/04 ; C07D333/24 ; C07D501/06
摘要：
A compound having the formula: ##EQU1## and a 7-amihocephalosporanic acid derivative having the formula: ##SPC1##Are reacted in a homogeneous aqueous solution of the reactants to prepare a reaction of the formula: ##SPC2##In the formulas, R may be H or other defined substituents such as carboxyl group; R.sub.1 is H, an alkyl of 1-4 carbons or other defined substitents; R.sub.2 is H or phenyl or when taken together with R.sub.1 form a defined cyclicradical; R.sub.3 is H or other defined substituents and M is an alkali metal cation, ammonium cation or H.