利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

6 条记录 (耗时 0.015 秒)

    Process for preparing cephalosporanic acid derivatives
    4.
    发明授权
    Process for preparing cephalosporanic acid derivatives 失效
    制备头孢菌酸衍生物的方法

    公开(公告)号：US4175185A

    公开(公告)日：1979-11-20

    申请号：US892179

    申请日：1978-03-31

    申请人： Shigeo Seki ,  Satoru Nakabayashi ,  Toshinori Saito ,  Shunzo Fukatsu ,  Shokichi Nakajima ,  Toshiyasu Ishimaru

    发明人： Shigeo Seki ,  Satoru Nakabayashi ,  Toshinori Saito ,  Shunzo Fukatsu ,  Shokichi Nakajima ,  Toshiyasu Ishimaru

    IPC分类号： C07D501/20 ,  C07D501/26

    CPC分类号： C07D501/26

    摘要： A process for preparing a cephalosporanic acid derivative or a 7-acylaminocephalosporanic acid derivative which comprises subjecting an esterifying agent to reaction in liquid sulfur dioxide in the presence of a base with an N-protected-cephalosporin C to obtain a diester, subjecting the diester to reaction in an inert solvent with an iminohalide forming agent to produce an iminohalide, subjecting the iminohalide with a lower alcohol to produce an iminoether, subjecting the product produced, after subjecting the iminoether to reaction with a reactive derivative of an organic acid, to hydrolysis and further eliminating the ester group of the carboxylic acid.

    摘要翻译： 一种制备头孢菌酸衍生物或7-酰氨基头孢烷酸衍生物的方法，其包括在碱存在下，用N-保护型头孢菌素C使酯化剂在液态二氧化硫中进行反应，得到二酯， 在惰性溶剂中与亚氨基卤化物形成剂反应以产生亚氨基卤化物，使亚氨基卤化物与低级醇反应生成亚氨基醚，使亚氨基醚与有机酸的反应性衍生物反应后生成的产物水解和 进一步消除羧酸的酯基。

    Method of and apparatus for detecting microorganisms
    5.
    发明授权
    Method of and apparatus for detecting microorganisms 失效
    检测微生物的方法和装置

    公开(公告)号：US5366858A

    公开(公告)日：1994-11-22

    申请号：US946775

    申请日：1992-09-18

    申请人： Naohisa Koizumi ,  Shokichi Nakajima ,  Naoki Yuguchi ,  Kazumi Tanaka

    发明人： Naohisa Koizumi ,  Shokichi Nakajima ,  Naoki Yuguchi ,  Kazumi Tanaka

    IPC分类号： G01N33/569 ,  G01N33/543 ,  G01N33/53

    CPC分类号： G01N33/56911

    摘要： The present invention provides a method of detecting microorganisms, comprising the step of converting physical forms of microorganisms by antigen-antibody reaction and successively measuring the information that shows the physical forms of the converted data, and the step of comparing a statistical pattern of the values thus measured and a reference statistical pattern of a control subjected to no antigen-antibody reaction, thus detecting the microorganisms of interest. A change in both patterns, i.e., no correspondence thereof, enables recognition of the presence of the microorganisms of interest.

    摘要翻译： 本发明提供了一种检测微生物的方法，包括通过抗原 - 抗体反应转化微生物的物理形式并连续测量显示转化数据的物理形式的信息的步骤，以及将值的统计模式 进行测定，并进行无抗原抗体反应的对照的参考统计学图谱，从而检测感兴趣的微生物。 两种图案的改变，即它们的对应关系，都能够识别感兴趣的微生物的存在。