发明授权
- 专利标题: Fluorodesulfurization of alkyl mercaptans or alkyl dithianes
- 专利标题(中): 烷基硫醇或烷基二噻烷的脱硫
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申请号: US663586申请日: 1976-03-04
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公开(公告)号: US4049708A公开(公告)日: 1977-09-20
- 发明人: Janos Kollonitsch , Stephen Marburg
- 申请人: Janos Kollonitsch , Stephen Marburg
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C227/16
- IPC分类号: C07C227/16 ; C07C101/10 ; A61K31/195
摘要:
Organic compounds containing a mercapto group or a dithiane moiety can be transformed into the analogous fluoro or difluoro compounds by reacting them with a halogenating reagent in liquid hydrogen fluoride, optionally containing boron trifluoride or antimony pentafluoride solution, at temperatures from about -80.degree. and 15.degree. C. The method may be descriptively termed "fluorodesulfurization".