发明授权
US4244958A Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid
失效
4,5-二氢-4-氧代呋喃-2-羧酸的降血脂衍生物
- 专利标题： Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid
- 专利标题（中）： 4,5-二氢-4-氧代呋喃-2-羧酸的降血脂衍生物
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申请号： US38028申请日： 1979-05-10
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公开(公告)号： US4244958A公开(公告)日： 1981-01-13
- 发明人: Ivo L. Jirkovsky , Dushan Dvornik , Mitchell N. Cayen
- 申请人： Ivo L. Jirkovsky , Dushan Dvornik , Mitchell N. Cayen
- 申请人地址： NY New York
- 专利权人： American Home Products Corporation
- 当前专利权人： American Home Products Corporation
- 当前专利权人地址： NY New York
- 主分类号： C07C29/42
- IPC分类号： C07C29/42 ; C07C45/31 ; C07D307/68 ; C07D309/36 ; A61K31/34 ; A61K31/445 ; C07D213/55
摘要：
Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid characterized by having two substituents at position 5 and in addition being optionally further substituted at position 3 with a lower alkyl group, as well as esters therefor are disclosed. The foregoing compounds are useful hypolipidemic agents in a mammal. Novel methods for the preparation of these compounds also are disclosed.
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