发明授权
US4259336A 4-Hydroxy-2H-[1]-benzothieno
[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof
失效
4-羟基-2H- [1] - 苯并噻吩并[2,3-e] -1,2-噻嗪-3-甲酰胺-1,1-二氧化物及其盐
- 专利标题: 4-Hydroxy-2H-[1]-benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof
- 专利标题(中): 4-羟基-2H- [1] - 苯并噻吩并[2,3-e] -1,2-噻嗪-3-甲酰胺-1,1-二氧化物及其盐
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申请号: US86743申请日: 1979-10-22
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公开(公告)号: US4259336A公开(公告)日: 1981-03-31
- 发明人: Wolfhard Engel , Gunter Trummlitz , Ernst Seeger , Walter Haarmann , Gunther Engelhardt , Rainer Zimmermann
- 申请人: Wolfhard Engel , Gunter Trummlitz , Ernst Seeger , Walter Haarmann , Gunther Engelhardt , Rainer Zimmermann
- 申请人地址: DEX Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim GmbH
- 当前专利权人: Boehringer Ingelheim GmbH
- 当前专利权人地址: DEX Ingelheim am Rhein
- 优先权: DEX2838377 19780902
- 主分类号: A61K31/54
- IPC分类号: A61K31/54 ; A61P9/08 ; A61P9/10 ; A61P29/00 ; C07D333/70 ; C07D513/04 ; A61K31/38
摘要:
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen or alkyl of 1 to 3 carbon atoms; R.sub.2 is hydrogen or alkyl of 1 to 3 carbon atoms; andR.sub.3 is aromatic hydrocarbyl of 6 to 10 carbon atoms or an aromatic heterocycle of 2 to 9 carbon atoms and 1 to 2 nitrogen atoms and/or an oxygen or a sulfur atom, where each of said aromatic substituents may in turn be substituted with one or two alkyls of 1 to 6 carbon atoms, halogen, hydroxyl, trifluoromethyl, halophenyl or alkoxy of 1 to 3 carbon atoms;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases; the compounds as well as their salts are useful as analgesics, antipyretics, antithrombotic and antiphlogistics.
公开/授权文献
- USD433653S Exterior surface configuration of a motor vehicle 公开/授权日:2000-11-14
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