A pneumatic run flat tire for motorcycles having a high handling stability during straight and zigzag runnings, cornering stability and durability, even when the tire is punctured while running and the pneumatic pressure inside of the tire becomes equal to atmospheric pressure. The run flat tire has a pair of sidewall-reinforcing layers, each comprising an elastic filler extending from an end location adjacent a bead core in a bead portion to the other end location in a tread portion through a sidewall portion of the tire, the elastic filler being reinforced with at least two reinforcing plies, one of which extends along one side surface of the elastic filler toward the tread portion, and then, additionally extends into the tread portion, and the other one of which extends along the other side surface of the elastic filler toward the bead portion, and the, additionally extends into the tread portion.