发明授权
US4271073A 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-one
失效
6-取代的9-（2-羟乙基）-1,2,3,4-四氢咔唑-1-酮
- 专利标题： 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-one
- 专利标题（中）： 6-取代的9-（2-羟乙基）-1,2,3,4-四氢咔唑-1-酮
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申请号： US98498申请日： 1979-11-29
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公开(公告)号： US4271073A公开(公告)日： 1981-06-02
- 发明人: Heinz Bender , Rudi Beyerle , Karl-Heinz Keil , Heinz G. Greve , Kuno Reh
- 申请人： Heinz Bender , Rudi Beyerle , Karl-Heinz Keil , Heinz G. Greve , Kuno Reh
- 申请人地址： DEX Frankfurt am Main-Fechenheim
- 专利权人： Cassella Aktiengesellschaft
- 当前专利权人： Cassella Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main-Fechenheim
- 主分类号： C07D209/88
- IPC分类号： C07D209/88 ; C07D487/06 ; C07D241/38
摘要：
The present invention relates to new, pharmacologically valuable 2,4,5,6-tetrahydro-1H-pyrazino-[3,2,1-jk]-carbazoles substituted in the 8-position having the formula I ##STR1## wherein R stands for an alkyl or alkoxy group having 1 to 4 carbon atoms or a fluorine, chlorine or bromine atom comprising reacting a 6,9-disubstituted 1,2,3,4-tetrahydrocarbazol-1-one of the formula II ##STR2## and X denotes a bromine, chlorine or iodine atom or the radical of the formula defined --O--SO.sub.2 --R' and R' is an alkyl radical having 1 to 3 carbon atoms, phenyl or tolyl, with ammonia.
公开/授权文献
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