发明授权
- 专利标题: Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
- 专利标题(中): 二氯吡咯持续释放形式,包括漆包衣颗粒及其制备
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申请号: US221834申请日: 1980-12-31
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公开(公告)号: US4367217A公开(公告)日: 1983-01-04
- 发明人: Peter Gruber , Rolf Brickl , Gerhard Bozler , Herbert Stricker
- 申请人: Peter Gruber , Rolf Brickl , Gerhard Bozler , Herbert Stricker
- 申请人地址: DEX Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim GmbH
- 当前专利权人: Boehringer Ingelheim GmbH
- 当前专利权人地址: DEX Ingelheim am Rhein
- 优先权: DEX3000979 19800112
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K9/22 ; A61K9/24 ; A61K9/48 ; A61K9/50 ; A61K9/52 ; A61K9/54 ; A61K9/56 ; A61K31/505 ; A61P9/08 ; A61P9/10 ; A61K9/26
摘要:
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.
公开/授权文献
- US5547228A Cylindrical corrosion barrier for pipe connections 公开/授权日:1996-08-20
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