发明授权
- 专利标题： 3'-Deamino-3'-morpholino carminomycin
- 专利标题（中）： 3'-脱氨基-3'-吗啉代卡金霉素
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申请号： US357970申请日： 1982-03-15
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公开(公告)号： US4374980A公开(公告)日： 1983-02-22
- 发明人: Hamao Umezawa , Tomio Takeuchi , Kuniaki Tatsuta , Yoshikazu Takahashi
- 申请人： Hamao Umezawa , Tomio Takeuchi , Kuniaki Tatsuta , Yoshikazu Takahashi
- 申请人地址： JPX Tokyo
- 专利权人： Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
- 当前专利权人： Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX56-44159 19810327
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; A61K31/7028 ; A61K31/7034 ; A61K31/704 ; A61P31/04 ; A61P35/00 ; C07H15/252 ; A61K31/71 ; C07H15/24
摘要：
Disclosed is 3'-deamino-3'-morpholino-carminomycin, a new anthracycline glycoside having both antimicrobial and antitumor activity. Also disclosed is a new N-alkylation procedure for preparing the above compound as well as the known anthracyclines, 3'-deamino-3'-morpholino-adriamycin and 3'-deamino-3'-morpholino-daunomycin, in high yield.