发明授权
- 专利标题: Alanyl-2-(5-hydroxy-2-oxo-pyrrolidin-3-yl)glycine
- 专利标题(中): 丙酰基-2-(5-羟基-2-氧代 - 吡咯烷-3-基)甘氨酸
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申请号: US526051申请日: 1983-08-23
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公开(公告)号: US4465844A公开(公告)日: 1984-08-14
- 发明人: Satoshi Horii , Hiroshi Fukase , Eiji Higashide
- 申请人: Satoshi Horii , Hiroshi Fukase , Eiji Higashide
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX56-10544 19810126
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07C67/00 ; C07C231/00 ; C07C231/12 ; C07D207/40 ; C07D207/416 ; C07K1/113 ; C07K5/06 ; C07K14/195 ; C07K14/41 ; C07D207/26 ; A61K31/40
摘要:
The peptide compound represented by the formula: ##STR1## which is useful as a germicide or disinfectant, is produced by reducing a compound of the formula: ##STR2## wherein Y is amino group which may optionally be protected; R.sup.1 is hydrogen or protective group; and R.sup.2 is hydrogen or protective group; and subjecting the reduction product compound to deprotection reaction when required. A compound of the formula: ##STR3## wherein Z is amino group which may optionally be protected; R.sup.1 is hydrogen or protective group; and R.sup.2 is hydrogen or protective group, is a useful as intermediate for production of the first-mentioned compound.
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