发明授权
US4500529A Method of treating cardiac disorders with
N-(aryloxyalkyl)-N'-(aminoalkyl)ureas
失效
用N-（芳氧基烷基）-N' - （氨基烷基）脲处理心脏病的方法
- 专利标题： Method of treating cardiac disorders with N-(aryloxyalkyl)-N'-(aminoalkyl)ureas
- 专利标题（中）： 用N-（芳氧基烷基）-N' - （氨基烷基）脲处理心脏病的方法
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申请号： US492534申请日： 1983-05-09
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公开(公告)号： US4500529A公开(公告)日： 1985-02-19
- 发明人: James R. Shanklin, Jr. , Christopher P. Johnson, III
- 申请人： James R. Shanklin, Jr. , Christopher P. Johnson, III
- 申请人地址： VA Richmond
- 专利权人： A. H. Robins Company, Incorporated
- 当前专利权人： A. H. Robins Company, Incorporated
- 当前专利权人地址： VA Richmond
- 主分类号： C07C43/225
- IPC分类号： C07C43/225 ; C07C275/14 ; C07C335/08 ; C07D209/48 ; C07D295/13 ; A61K31/535 ; A61K31/17
摘要：
N-(Aryloxyalkyl)-N'-(aminoalkyl)ureas and thioureas having the formula: ##STR1## wherein R.sup.1 and R.sup.2 are hydrogen, loweralkyl, cycloalkyl, phenyl or phenyllower alkyl, and R.sup.3 and R.sup.4 are hydrogen, loweralkyl, phenyl and phenylalkyl or R.sup.3 and R.sup.4 taken together with the adjacent nitrogen form a heterocyclic residue are disclosed in a method of suppressing cardiac arrhythmias.
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