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21 条记录 (耗时 0.024 秒)

    S-aminoalkyl-s-arylsulfoximines as antiarrhythmic agents
    7.
    发明授权
    S-aminoalkyl-s-arylsulfoximines as antiarrhythmic agents 失效
    S-氨基烷基-S-芳基亚磺酰亚胺作为抗心律失常药

    公开(公告)号：US5187189A

    公开(公告)日：1993-02-16

    申请号：US643364

    申请日：1991-01-22

    申请人： Mark R. Hellberg ,  James R. Shanklin, Jr.

    发明人： Mark R. Hellberg ,  James R. Shanklin, Jr.

    IPC分类号： C07C381/10 ,  C07D295/088

    CPC分类号： C07D295/088 ,  C07C381/10

    摘要： This invention discloses novel sulfoximines having the formula: ##STR1## where Z is C.sub.1 -C.sub.6 alkylene and Y is alkyl, arylalkyl, acyl, carbamoyl, sulfonyl or alkoxycarbonyl. The invention compounds are useful in the treatment of Class II arrhythmia.

    摘要翻译： 本发明公开了具有下式的新型磺酰亚胺：其中Z为C1-C6亚烷基，Y为烷基，芳基烷基，酰基，氨基甲酰基，磺酰基或烷氧基羰基。 本发明化合物可用于治疗II级心律失常。

    Lubricating oil additives
    9.
    发明授权
    Lubricating oil additives 失效
    润滑油添加剂

    公开(公告)号：US6071862A

    公开(公告)日：2000-06-06

    申请号：US329433

    申请日：1999-06-10

    申请人： James R. Shanklin, Jr. ,  Naresh C. Mathur

    发明人： James R. Shanklin, Jr. ,  Naresh C. Mathur

    IPC分类号： C10M159/12

    CPC分类号： C10M159/12 ,  C10M2205/00 ,  C10M2205/02 ,  C10M2205/026 ,  C10M2205/04 ,  C10M2207/10 ,  C10M2207/129 ,  C10M2207/34 ,  C10M2209/084 ,  C10M2209/086 ,  C10M2215/04 ,  C10M2215/042 ,  C10M2215/22 ,  C10M2215/221 ,  C10M2215/225 ,  C10M2215/226 ,  C10M2215/26 ,  C10M2215/30 ,  C10M2217/046 ,  C10M2217/06 ,  C10M2227/00 ,  C10N2240/10 ,  C10N2240/101 ,  C10N2240/104 ,  C10N2240/106

    摘要： A composition, comprising from about 20% to about 80% by weight of a diluent, prepared by reacting a mixture comprising(A) an esterified carboxy-containing interpolymer, said interpolymer being derived from at least two monomers, (i) one of said monomers being at least one of an aliphatic olefin containing from 2 to about 30 carbon atoms and a vinyl aromatic monomer and (ii) the other of said monomers being at least one alpha, beta-unsaturated acylating agent, and having, before esterification, M.sub.n determined by gel permeation chromatography ranging from about 8,000 to about 350,000, wherein from about 80% to about 99% of the carboxylic groups of said intelpolymer are esterified, wherein from about 80 to about 100% of the ester groups contain from 8 to about 23 carbon atoms and from 0 to about 20% of the ester groups contain from 2 to 7 carbon atoms, and(B) a hydrocarbyl substituted carboxylic acid or functional derivative thereof wherein the hydrocarbyl group comprises from about 10 to about 400 carbon atoms, with(C) an amine having an average of more than 1 condensable N--H groups, wherein from about 0 to about 95% of the diluent is present during the reacting and the product obtained from said reacting is further combined with additional diluent such that the total diluent comprises from about 20% to about 80% by weight of the total weight of the composition. Depending upon the relative amounts of reactant (A) and (B) used, a composition which acts primarily as a viscosity improver with dispersant properties (DVM) or primarily as a dispersant with viscosity improving properties (VMD)may be prepared or compositions with properties intermediate between these.

    摘要翻译： 一种组合物，其包含约20％至约80％重量的稀释剂，其通过使包含（A）含酯化羧基的互聚物，所述互聚物衍生自至少两种单体的混合物，（i）所述 单体是含有2至约30个碳原子的脂族烯烃和乙烯基芳族单体中的至少一种，和（ii）所述单体中的另一种是至少一种α，β-不饱和酰化剂，并且在酯化前具有+ E，ovs M + EE n通过约8,000至约350,000的凝胶渗透色谱测定，其中约80％至约99％的所述智力聚合物的羧基被酯化，其中约80至约100％的酯 基团含有8至约23个碳原子，0至约20％的酯基含有2至7个碳原子，和（B）烃基取代的羧酸或其官能衍生物，其中烃基包括 （C）具有平均多于1个可冷凝NH基团的胺，其中在反应期间存在约0至约95％的稀释剂，并且从所述反应获得的产物为 进一步与额外的稀释剂组合，使得总稀释剂占组合物总重量的约20重量％至约80重量％。 取决于所用的反应物（A）和（B）的相对量，可以制备主要作为粘度改进剂的分散剂性能（DVM）或主要作为具有粘度改进性能（VMD）的分散剂的组合物或具有性质的组合物 这些之间的中间。