发明授权
US4581355A 3-indolecarboxamides for control of circulatory diseases
失效
3-indolecarboxamides用于控制循环系统疾病
- 专利标题: 3-indolecarboxamides for control of circulatory diseases
- 专利标题(中): 3-indolecarboxamides用于控制循环系统疾病
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申请号: US680727申请日: 1984-12-12
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公开(公告)号: US4581355A公开(公告)日: 1986-04-08
- 发明人: Tetsuya Tahara , Tsuguo Ikebe , Yutaka Maruyama , Osamu Yaoka , Yohji Miura
- 申请人: Tetsuya Tahara , Tsuguo Ikebe , Yutaka Maruyama , Osamu Yaoka , Yohji Miura
- 申请人地址: JPX Osaka
- 专利权人: Yoshitomi Pharmaceutical Industries, Ltd.
- 当前专利权人: Yoshitomi Pharmaceutical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX58-251149 19831228
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/4427 ; A61K31/445 ; A61K31/55 ; A61P9/00 ; A61P9/04 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P25/28 ; A61P43/00 ; C07D401/12 ; C07D403/12
摘要:
3-Indolecarboxamide compounds of the formula: ##STR1## inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R.sup.1 is hydrogen or C.sub.1-4 alkyl; each of R.sup.2 and R.sup.3 is hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, benzyloxy, C.sub.2-6 alkanoyloxy or hydroxy; R.sup.4 is hydrogen or C.sub.1-4 alkyl; R.sup.5 is hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or hydroxy; R.sup.6 is hydrogen or C.sub.1-4 alkyl; X is oxygen, sulfur or direct bond; each of k and m is an integer of 1 to 3; and n is 1 or 2, are useful as drug for the prevention and treatment of various circulatory diseases.
公开/授权文献
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