发明授权
- 专利标题: Heterocyclic derivatives
- 专利标题(中): 杂环衍生物
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申请号: US567005申请日: 1983-12-30
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公开(公告)号: US4585781A公开(公告)日: 1986-04-29
- 发明人: David Bays , Roger Hayes , Philip Blatcher
- 申请人: David Bays , Roger Hayes , Philip Blatcher
- 申请人地址: GB2 London
- 专利权人: Glaxo Group Limited
- 当前专利权人: Glaxo Group Limited
- 当前专利权人地址: GB2 London
- 优先权: GBX8237069 19821231; GBX8308171 19830324
- 主分类号: C07D257/04
- IPC分类号: C07D257/04 ; C07D405/12 ; C07D417/12 ; C07D403/12 ; A61K31/415 ; A61K31/425
摘要:
This invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and hydrates thereof, in which R.sub.1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group;R.sub.2 represents a hydrogen atom or an alkyl or alkenyl group or C.sub.2-6 alkyl group substituted by a hydroxy or alkoxy group;X represents a sulphur atom or NH;Y represents an oxygen or sulphur atom or a bond;m represents 1, 2 or 3; andn represents 2, 3 or 4.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.
公开/授权文献
- US5665140A Method for the production of iron carbide 公开/授权日:1997-09-09