发明授权
- 专利标题： Penem derivatives, and composition containing them
- 专利标题（中）： Penem衍生物和含有它们的组合物
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申请号： US494570申请日： 1983-05-13
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公开(公告)号： US4613595A公开(公告)日： 1986-09-23
- 发明人: Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
- 申请人： Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
- 申请人地址： JPX Tokyo
- 专利权人： Sankyo Company Limited
- 当前专利权人： Sankyo Company Limited
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX57-81067 19820514
- 主分类号： C07D205/08
- IPC分类号： C07D205/08 ; A61K31/397 ; A61K31/505 ; A61P31/04 ; C07D205/09 ; C07D207/12 ; C07D477/00 ; C07D477/20 ; C07D499/88 ; C07D499/897 ; C07F7/18 ; C07D499/00 ; A61K31/425
摘要：
Compounds of formula (I): ##STR1## (wherein R.sup.1 represents a C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.3 alpha-hydroxyalkyl group;R.sup.2 represents a hydrogen atom, a substituted or unsubstituted alkyl group or a cycloalkyl group;R.sup.3 represents a hydrogen atom or an alkyl group; and n is 1 or 2) and their salts and esters have valuable antibiotic activity and can be used for the treatment of diseases caused by a wide range of pathogenic microorganisms.
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