发明授权
- 专利标题： Dopamine-.beta.-hydroxylase inhibitors
- 专利标题（中）： 多巴胺-β-羟化酶抑制剂
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申请号： US793513申请日： 1985-10-31
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公开(公告)号： US4628059A公开(公告)日： 1986-12-09
- 发明人: Joseph A. Finkelstein , Carl Kaiser , Lawrence I. Kruse
- 申请人： Joseph A. Finkelstein , Carl Kaiser , Lawrence I. Kruse
- 申请人地址： PA Philadelphia
- 专利权人： SmithKlein Beckman Corporation
- 当前专利权人： SmithKlein Beckman Corporation
- 当前专利权人地址： PA Philadelphia
- 主分类号： A61K31/41
- IPC分类号： A61K31/41 ; A61P1/04 ; A61P7/10 ; A61P9/04 ; A61P9/08 ; A61P9/12 ; A61P43/00 ; C07D249/08 ; C07D249/12
摘要：
Potent dopamine-.beta.-hydroxylase inhibitors having the Formula ##STR1## that are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.
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