发明授权
US4737466A N-acyldihydroresorufin derivatives, processes for their preparation,
reagents containing them and the use thereof for determining hydrogen
peroxide, peroxidate-acting compounds or peroxidase
失效
N-酰基二氢代芬芬衍生物,其制备方法,含有它们的试剂及其用于测定过氧化氢,过氧化物作用化合物或过氧化物酶
- 专利标题: N-acyldihydroresorufin derivatives, processes for their preparation, reagents containing them and the use thereof for determining hydrogen peroxide, peroxidate-acting compounds or peroxidase
- 专利标题(中): N-酰基二氢代芬芬衍生物,其制备方法,含有它们的试剂及其用于测定过氧化氢,过氧化物作用化合物或过氧化物酶
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申请号: US884372申请日: 1986-07-11
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公开(公告)号: US4737466A公开(公告)日: 1988-04-12
- 发明人: Christian Klein , Herbert Von Der Eltz , Rupert Herrmann , Martina Junius
- 申请人: Christian Klein , Herbert Von Der Eltz , Rupert Herrmann , Martina Junius
- 申请人地址: DEX Mannheim
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX3526566 19850725
- 主分类号: G01N33/50
- IPC分类号: G01N33/50 ; C07D265/38 ; C12Q1/20 ; C12Q1/26 ; C12Q1/28 ; G01N33/52 ; G01N33/72
摘要:
The present invention provides N-acylidihydroresorufin derivatives of the general formula: ##STR1## wherein R.sup.1 is a lower alkyl, aryl or aralkyl radical, which can be substituted by carboxyl or sulphonic acid residues, R.sup.2, R.sup.3 and R.sup.4, which can be the same or different, are hydrogen or halogen atoms or lower alkyl or lower alkoxy radicals, Y is an --NR.sup.5 R.sup.6 or --OR.sup.7 group, wherein R.sup.5 and R.sup.6 are, in each case, hydrogen atoms or lower alkyl radicals, which can be substituted by carboxyl or sulphonic acid residues, or together represent a hydrocarbon bridge optionally interrupted by hereto atoms and R.sup.7 is a lower alkyl radical which can be substituted by a lower alkoxy or poly-lower alkoxy radical.
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