A tamper indicating closure for use with a container having a neck with an opening in which at least a portion of the closure is transparent. A destructible seal is bonded to the container neck providing a hermetic seal which is visible through the closure to indicate package integrity or tampering. In some embodiments, a transparent insert member is provided through which the seal element is visible, and after removal of the seal element, the insert member serves to reseal the closure to the container neck. In some embodiments, access is obtained to the container by unthreading and removing the closure from the container neck and puncturing the destructible seal element. In other embodiments, the seal element is bonded to the flat closure top or the insert so that the seal element is fractured upon initial opening movement of the closure to remove it from the container neck.