发明授权
- 专利标题： Detectably labeled cephalosporin assay for beta-lactamase
- 专利标题（中）： 可检测标记的β-内酰胺酶的头孢菌素测定
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申请号： US768832申请日： 1985-08-23
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公开(公告)号： US4764462A公开(公告)日： 1988-08-16
- 发明人: Reinhard Bredehorst , Abdolhossen Talebian , Charles F. Hammer , Carl-Wilhelm Vogel
- 申请人： Reinhard Bredehorst , Abdolhossen Talebian , Charles F. Hammer , Carl-Wilhelm Vogel
- 申请人地址： DC Washington
- 专利权人： Georgetown University
- 当前专利权人： Georgetown University
- 当前专利权人地址： DC Washington
- 主分类号： C12Q1/34
- IPC分类号： C12Q1/34 ; G01N33/532 ; C12N9/96 ; C12Q1/02 ; C12Q1/04 ; C12Q1/06 ; C12Q1/10
摘要：
This invention provides for a cephalosporin immobilized on a solid phase support comprising a beta-lactamase releasable, detectably labeled substituent at the 3-position thereof.This invention also provides for an assay for detecting the presence of beta-lactamase enzyme in a sample comprising:(a) immobilizing a cephalosporin on a solid phase support wherein at the 3-position of said cephalosporin is a detectably labeled substituent releasable by beta-lactamase;(b) contacting said sample with the immobilized cephalosporin of step (a); and,(c) detecting the released substituent.
公开/授权文献
- US5916945A Antistatic and adherent compositions based on polyamide 公开/授权日：1999-06-29
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