发明授权
US4810725A 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceutical
compositions and use
失效
1-芳氧基-3-(取代的氨基烷基氨基)-2-丙醇,药物组合物和用途
- 专利标题: 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceutical compositions and use
- 专利标题(中): 1-芳氧基-3-(取代的氨基烷基氨基)-2-丙醇,药物组合物和用途
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申请号: US918240申请日: 1986-10-14
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公开(公告)号: US4810725A公开(公告)日: 1989-03-07
- 发明人: John J. Baldwin , Gerald S. Ponticello , Sandor L. Varga
- 申请人: John J. Baldwin , Gerald S. Ponticello , Sandor L. Varga
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C279/28
- IPC分类号: C07C279/28 ; C07C335/16 ; C07C335/18 ; C07D239/42 ; C07D253/075 ; C07D285/10 ; C07D295/215 ; A61K31/17 ; A61K31/275 ; C07C127/00
摘要:
1-Aryloxy-3-(substituted aminoalkylamino)-2-propanols and pharmaceutically acceptable salts thereof have .beta.-adrenergic blocking activity with some cardioselectivity and hence are useful as anti-hypertensive, antianginal, antiarrhythmic and cardioprotective agents and in the treatment of elevated intraocular pressure such as glaucoma.
公开/授权文献
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