发明授权
US4814329A Antihyperlipoproteinemic 5-substituted sulfur-containing benzimidazole
derivatives
失效
抗高脂蛋白血症5-取代含硫苯并咪唑衍生物
- 专利标题: Antihyperlipoproteinemic 5-substituted sulfur-containing benzimidazole derivatives
- 专利标题(中): 抗高脂蛋白血症5-取代含硫苯并咪唑衍生物
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申请号: US840424申请日: 1986-03-17
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公开(公告)号: US4814329A公开(公告)日: 1989-03-21
- 发明人: Kalmen Harsanyi , Andrea Maderspach , Andres Javor , Gyorgy Hajos , Gyorgy Fekete , Laslo Szporny , Peter Tetenyi , Katalin Csomor , Egon Karpati , Bela Hegedus , Marta Kapolnas nee Pap , Marta Szollosy , Anna Kallay nee Sohonyai
- 申请人: Kalmen Harsanyi , Andrea Maderspach , Andres Javor , Gyorgy Hajos , Gyorgy Fekete , Laslo Szporny , Peter Tetenyi , Katalin Csomor , Egon Karpati , Bela Hegedus , Marta Kapolnas nee Pap , Marta Szollosy , Anna Kallay nee Sohonyai
- 申请人地址: HUX Budapest
- 专利权人: Richter Gedeon Vegyeszeti Gyar R.T.
- 当前专利权人: Richter Gedeon Vegyeszeti Gyar R.T.
- 当前专利权人地址: HUX Budapest
- 优先权: HUX892/85 19850311
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61K31/4184 ; A61K31/445 ; A61K31/454 ; A61K31/535 ; A61K31/5355 ; A61K31/54 ; A61K31/541 ; A61P3/06 ; C07D235/28 ; C07D513/04 ; A61K31/55 ; C07D413/12 ; C07D417/12
摘要:
The invention relates to novel, sulfur-containing 5-substituted benzimidazole derivatives of formula I ##STR1## and acid-addition salts thereof antihyperlipoproteinemic action, a process for preparing the same, pharmaceutical formulations comprising the novel compound as active ingredient and a method for inhibiting atherosclerosis, trombus formation and treating hyperlipoproteinemic diseases.
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