发明授权
- 专利标题： Diphenylpyridine compounds, processes for the preparation thereof and composition comprising the same
- 专利标题（中）： 二苯基吡啶化合物，其制备方法和包含其的组合物
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申请号： US940923申请日： 1986-12-12
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公开(公告)号： US4831030A公开(公告)日： 1989-05-16
- 发明人: Hisashi Takasugi , Atsushi Kuno , Hiroyoshi Sakai , Yoshie Sugiyama , Takao Takaya
- 申请人： Hisashi Takasugi , Atsushi Kuno , Hiroyoshi Sakai , Yoshie Sugiyama , Takao Takaya
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX8530602 19851212
- 主分类号： C07D237/10
- IPC分类号： C07D237/10 ; A61K31/435 ; A61K31/44 ; A61K31/4418 ; A61K31/445 ; A61K31/455 ; A61K31/495 ; A61K31/50 ; A61K31/535 ; A61K31/54 ; A61P9/00 ; A61P25/28 ; C07D211/78 ; C07D213/26 ; C07D213/30 ; C07D213/36 ; C07D213/38 ; C07D213/80 ; C07D213/82 ; C07D237/04 ; C07D237/08 ; C07D237/24 ; C07D471/04
摘要：
The invention relates to compounds for treatment of hypertension, and cardiovascular and cerebrovascular diseases, which compounds are of the formula: ##STR1## wherein R.sup.1 is piperazinyl(lower)alkyl, carbamoyl substituted with piperazinyl(lower)alkyl, or piperazinylcarbonyl, in each of which a piperazinyl group may be substituted with lower alkyl, andR.sup.3 is hydrogen or halogen;R.sup.2 is phenyl substituted with nitro, andR.sup.4 is lower alkyl or halo(lower)alkyl; orR.sup.2 is lower alkyl, andR.sup.4 is phenyl substitured with nitro;and a pharmaceutically acceptable salt thereof.
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