发明授权
- 专利标题: Aryl and heteroaryl substituted cycloalkyl compounds
- 专利标题(中): 芳基和杂芳基取代的环烷基化合物
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申请号: US213043申请日: 1988-06-27
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公开(公告)号: US4843081A公开(公告)日: 1989-06-27
- 发明人: John R. Regan , Jeffrey N. Barton , John T. Suh , Jerry W. Skiles
- 申请人: John R. Regan , Jeffrey N. Barton , John T. Suh , Jerry W. Skiles
- 申请人地址: PA Fort Washington
- 专利权人: Rorer Pharmaceutical Corporation
- 当前专利权人: Rorer Pharmaceutical Corporation
- 当前专利权人地址: PA Fort Washington
- 主分类号: C07C255/46
- IPC分类号: C07C255/46 ; C07D209/08 ; C07D215/06 ; C07D217/02
摘要:
A and A' are each hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, hydroxy or aryloxy;X is cyano, nitro, COOR, SR, SOR or SOOR;R is H, C.sub.1-6 alkyl or aryl;n n' and n" are each 0 to 4; andm, m' and m" are each 1 to 4, have calcium channel blocking activity.